Fig. 7.

48-hour cleaved caspase-3 in podocytes. a Cleaved caspase-3 protein in NG (5.5 mM glucose), HG (40 mM glucose) and HG + ALI (40 mM glucose + 20 mM ALI), n = 3. b In NG, ALI did not reduce cleaved caspase-3 protein, nor was cleaved caspase-3 protein changed by isotonic mannitol (5.5 mM glucose + 34.5 mM mannitol, n = 3 in each group). c TUNEL staining showed a significant increment in apoptotic podocytes in HG vs. NG, which was significantly attenuated by ALI. * p < 0.05 vs. HG; ** p < 0.05 vs. NG.