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Anaphylaxis in peanut-sensitized Collaborative Cross strains following peanut challenge. Oral and IP challenges revealed Collaborative Cross strains that are non-reactors (A, D), mild reactors (B, E) and severe reactors (C, F) as measured by decreased body temperature. Challenges were repeated with an IP reactor control (G), a non-reactor control (H), and oral reactors (I, J).
