Table 2. Effects of maternal and fetal rs746039 (G) on fetal weight and head circumference at 27 weeks and 6 days gestation.
Fetal weight z-score (27 weeks and 6 days) |
Head circumference z-score (27 weeks and 6 days) |
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---|---|---|---|---|---|---|---|---|---|
Model | Genotype tested | Beta | s.e. | P | Effect | Beta | s.e. | P | Effect |
Model 1a | Fetal | 0.09 | 0.16 | 0.55 | ++- | 0.09 | 0.16 | 0.57 | ++- |
Model 1b | Maternal | -0.13 | 0.15 | 0.40 | -+- | -0.27 | 0.16 | 0.09 | -+- |
Model 2a | Fetal | -0.06 | 0.22 | 0.80 | ++- | -0.08 | 0.23 | 0.74 | ++- |
Maternal | -0.18 | 0.17 | 0.27 | -+- | -0.35 | 0.17 | 0.04 | -+- | |
Model 2b | Fetal | -0.18 | 0.28 | 0.51 | +?- | -0.13 | 0.28 | 0.64 | +?- |
Maternal | -0.45 | 0.20 | 0.02 | -?- | -0.55 | 0.19 | 0.004 | -?- |
Model 1a: fetal genotype + fetal sex. Model 1b: maternal genotype + fetal sex. Model 2: fetal genotype + maternal genotype + fetal sex (2a includes Whites, Blacks and Hispanics, 2b includes Whites and Hispanics). Effect: direction of effect based on meta-analysis with GWAMA (Whites, Blacks, Hispanics, respectively)