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. 2020 May 14;16(5):e1008747. doi: 10.1371/journal.pgen.1008747

Table 2. Effects of maternal and fetal rs746039 (G) on fetal weight and head circumference at 27 weeks and 6 days gestation.

    Fetal weight z-score
(27 weeks and 6 days)
Head circumference z-score
(27 weeks and 6 days)
Model Genotype tested Beta s.e. P Effect Beta s.e. P Effect
Model 1a Fetal 0.09 0.16 0.55 ++- 0.09 0.16 0.57 ++-
Model 1b Maternal -0.13 0.15 0.40 -+- -0.27 0.16 0.09 -+-
Model 2a Fetal -0.06 0.22 0.80 ++- -0.08 0.23 0.74 ++-
Maternal -0.18 0.17 0.27 -+- -0.35 0.17 0.04 -+-
Model 2b Fetal -0.18 0.28 0.51 +?- -0.13 0.28 0.64 +?-
  Maternal -0.45 0.20 0.02 -?- -0.55 0.19 0.004 -?-

Model 1a: fetal genotype + fetal sex. Model 1b: maternal genotype + fetal sex. Model 2: fetal genotype + maternal genotype + fetal sex (2a includes Whites, Blacks and Hispanics, 2b includes Whites and Hispanics). Effect: direction of effect based on meta-analysis with GWAMA (Whites, Blacks, Hispanics, respectively)