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. 2019 Apr 15;10(4):3623–3632. doi: 10.19102/icrm.2019.100403

Table 1:

Rate and Detection Cutoff Values Used in MADIT-RIT10 and ADVANCE III11

MADIT-RIT (high-rate arm) settings
Rate Cutoff Duration Cutoff Therapy
VT zone 170 bpm Monitoring only
VF zone 200 bpm 2.5 seconds ATP + shock
MADIT-RIT (duration-delay arm) settings
Rate Cutoff Delay Therapy
VT-1 zone 170 bpm 60 seconds ATP + shock
VT-2 zone 200 bpm 12 seconds ATP + shock
VF zone 250 bpm 2.5 seconds ATP + shock
ADVANCE III settings
Rate Cutoff Detection Cutoff Therapy
VT zone 150 bpm Monitoring only
VF zone 188 bpm 30/40 detection intervals ATP while charging; shock

ATP: antitachycardia pacing; VF: ventricular fibrillation; VT: ventricular tachycardia.