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. 2020 May 5;22(1):105–116. doi: 10.3892/mmr.2020.11124

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Differential expression of lncRNAs, miRNAs and mRNAs. (A) Volcano plot and (B) heatmap of DElncRNAs. (C) Volcano plot and (D) heatmap of DEmiRNAs. (E) Volcano plot and (F) heatmap of DEmRNAs. In the volcano plots and heatmaps, red represents upregulated genes, green represents downregulated genes and black represents unchanged genes. A total of 442 DElncRNAs (234 upregulated and 208 downregulated), 214 DEmiRNAs (120 upregulated and 94 downregulated) and 4,912 DEmRNAs (2,056 upregulated and 2,856 downregulated) were identified according to the cut-off criteria (|log2 fold-change|>1 and FDR <0.05). DE, differentially expressed; lncRNA, long non-coding RNA; miRNA, microRNA; FDR, false discovery rate.