Table 1:
Substrate Localization and Distribution in Structural Cardiomyopathy
| Ischemic Cardiomyopathy | Nonischemic Dilated Cardiomyopathy | ARVC/D | Cardiac Sarcoidosis | HOCM | Chagas Disease | |
|---|---|---|---|---|---|---|
| Substrate | Subendocardial | Midmyocardial/epicardial | Subepicardial | Nodular, circumferential, subepicardial, and subendocardial | Subendocardial | Epicardial > endocardial |
| Scar distribution | Focal | Patchy | Patchy | Focal anterior and posterior RV insertion points | Patchy | |
| Scar location | Coronary distribution | Basal anteroseptal and inferolateral LV regions | RV > LV; triangle of dysplasia* | Basal and mid-interventricular septum | LV apex and aneurysmal areas | Inferolateral and apical LV |
| Ablation approach | Endocardial | Endocardial/epicardial | Endocardial/epicardial | Endocardial > epicardial | Endocardial | Epicardial and endocardial |
ARVC/D: Arrhythmogenic right ventricular cardiomyopathy/dysplasia; HOCM: hypertrophic obstructive cardiomyopathy; LV: left ventricle/ventricular; RV: right ventricle/ventricular.
*Triangle of dysplasia: RV subtricuspid areas, apex, and infundibulum.