Table 1:
Studies Investigating Different Substrate Ablation Strategies for VT (continued)
| Ablation Method | Study | Complication(s) | Follow-up (Mean or Median) | VT Recurrence (%) | Mortality (%) |
|---|---|---|---|---|---|
| Linear ablation | Marchlinski et al. 200010 | 1 (stroke) | 8 (3–36) months | 4 (25%) | N/A |
| Soejima et al. 200172 | 4 (1 iliac artery dissection, 1 femoral artery pseudoaneurysm, 1 embolism to lower leg, 1 retroperitoneal hematoma) | 12 ± 6 months | 15 (37.5%) | 9 (22.5%); 5 noncardiac-related and unrelated to the procedure, 3 due to cardiac failure, 1 sudden death | |
| LP ablation | Volkmer et al. 200616 | 0 | 9 ± 4 months | 5 (21%) | 1 (4.2%) noncardiac cause |
| Arenal et al. 200373 | 0 | 26 ± 14 months | 7 (29%) | 2 (8%); 1 tamponade in hospital, 1 nonarrhythmogenic death | |
| Nogami et al. 200874 | N/A | 61 ± 38 months | 6 (33%) | 3 (17%); 2 heart failure, 1 malignancy | |
| Garcia et al. 200975 | 0 | 18 ± 13 months | 3 (23%) | N/A | |
| Bai et al. 201176 | 1 (groin hematoma) | 39 ± 4 months | 4 (15%) | 0 (0%) | |
| Vergara et al. 201277 | N/A | 13 ± 4 months | 10 (20%) | 1 (2%) heart failure | |
| Arenal et al. 201378 | 0 | 39 ± 21 months | 25 (42%) | 13 (22%); 6 heart failure, 3 recurrent incessant VT, 1 sudden cardiac death, 3 noncardiac-related | |
| LAVA | Jaïs et al. 201219 | 2 (1 cardiac tamponade, 1 RV perforation) | 22 (14–27) months | 32 (46%) | 13 (19%); 2 died within 24 hours from ablation, 1 PEA, 2 heart failure, 1 sudden death, 1 VT storm, 6 noncardiac-related |
| Wolf et al. 201820 | 12 (9 epicardial bleeding, 2 complete AV block, 1 acute heart failure) | 47 (33–82) months | 71(45%) | 40 (25%); 3 arrhythmia-related, 20 heart failure, 17 noncardiac-related | |
| Scar homogenization | Di Biase et al. 201511 | 3 (pericardial effusion) | 12 months | 9 (15.5%) | 5 (8.6%); 3 nonarrhythmic cardiac-related 2 noncardiac-related |
| Di Biase et al. 201217 | 1 (groin hematoma) | 21 (19–25) months | 8 (19%) | 1 (2%) noncardiac-related | |
| Scar dechanneling | Berruezo et al. 201238 | 1 (RV puncture) | 11 (6–24) months | 1 (9%) | 0 (0%) |
| Tung et al. 201381 | N/A | 11 (6–18) months | 3 (14%) | N/A | |
| Berruezo et al. 201582 | 7 (2 tamponade, 2 complete AV block, 2 pericardial effusion, 1 TIA, 1 PN palsy) | 21 (11–29) months | 20 (20%) | 9 (8.9%); 4 heart failure, 1 sudden cardiac death, 1 arrhythmic storm, 2 noncardiac-related, 1 unknown | |
| Fernández-Armenta et al. 2016102 | 0 | 22 ± 14 months | 10 (41.7%) | N/A | |
| Core isolation | Tzou et al. 201579 | 2 (1 arterial pseudoaneurysm, 1 transient hypotension) | 18 ± 9 months | 6 (14%) | 0 (0%) |
| MRI-based scar dechanneling | Andreu et al. 201783 | N/A | 20 ± 19 months | 10 (18.5%) | 0 (0%) |
AV: atrioventricular; CHF: congestive heart failure; DVT: deep vein thrombosis; LP: late potential; LAVA: local abnormal ventricular activity; MRI: magnetic resonance imaging; PN: phrenic nerve; RV: right ventricle/ventricular; TIA: transient ischemic attack.