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. Author manuscript; available in PMC: 2020 May 27.
Published in final edited form as: Toxicol Appl Pharmacol. 2019 May 14;378:114592. doi: 10.1016/j.taap.2019.05.011

Table 6.

Estimated percentagea of area represented by each peak in chromatogram in urine from Harlan Sprague Dawley rats and B6C3F1 mice following administration of [14C]DMAEa

Species/Sex Dose (mg/kg) Route DMAE (%) DMAE Oxide (%)
Rat/Male 10 Oral 95 5
Rat/Male 100 Oral 56 44
Rat/Male 500 Oral 34 66
Rat/Female 500 Oral 55 45
Rat/Male 10 IV 3 97
Mouse/Female 10 Oral 8 92
Mouse/Female 100 Oral 82 18
Mouse/Female 500 Oral 66 34
Mouse/Male 500 Oral 100 0
a

Number of animals per group varies between 3 and 5