Table 4. Scope of the Aldehydes for Thiohydroxyalkylation^a.

^aReaction conditions: unless otherwise noted, all reactions were carried out with 1 (0.2 mmol), 2a (0.3 mmol), 5 (0.8 mmol), Cs₂CO₃ (0.3 mmol), [Ir(dFCF₃ppy)₂dtbbpy]PF₆ (1 mol %) in 2 mL of DMSO, irradiation with blue LED (455 nm) at 25 °C for 24 h, and isolated yields were shown.

^b6 mmol scale.

^cParaformaldehyde (0.8 mmol) and DMSO (4 mL) were used.