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. 2020 May 7;5(9):e136095. doi: 10.1172/jci.insight.136095

Figure 6. Muscle function is improved in mdx mice following myofiber-specific deletion of Myomaker.

Figure 6

(A) Specific force of tibialis anterior (TA) muscle upon in situ muscle functional measurement (n = 7). (B) Upon repeated nerve stimulation to assay fatigability, mdx MymkfiberKO mice showed greater resistance to muscle fatigue (n = 7). (C) Immunofluorescence staining for myofiber type–specific myosin heavy chains revealed no change in myofiber type distribution of mdx MymkfiberKO TA muscle (n = 4–5). Statistical analyses and data presentation: (A and B) unpaired t test; *P < 0.05, **P < 0.01. Data are represented as mean ± SD. Scale bar: 50 μm (C).