Table 1.
Demographic, clinical, and laboratory information of the study population subgrouped according to different degrees of severity of dengue infection
| Severity grades | ||||
|---|---|---|---|---|
| Variables | DwoWS | DwWS | SD | P-value |
| Number of children | 19 | 36 | 21 | |
| Age (years), median (IQR) | 9 (7–13.2) | 10 (7–13) | 8 (4.5–8.7) | 0.040 |
| Gender (Male:female) | 14:05 | 22:14 | 11:10 | |
| WBC (×103), median (IQR) | 2.6 (2.2–3.4) | 3.3 (2.6–4.3) | 4.3 (3.3–4.6) | 0.060 |
| Hct (%), median (IQR) | 38.9 (36.6–41.3) | 40.4 (37.5–44) | 36.75 (33.9–38.3) | 0.461 |
| PLT (×103), median (IQR) | 110 (97.7–122) | 98.0 (68.0–121) | 18.5 (13.2–41.2) | 0.0001 |
| Torniquet test positive | 2 (25.0) | 6 (75.0) | 0 (0.0) | 0.002 |
| Fever | 19 (26.4) | 34 (47.2) | 19 (26.4) | 0.470 |
| Muscle pain | 11 (35.5) | 17 (54.8) | 3 (9.7) | 0.232 |
| Headache | 4 (19.0) | 15 (71.5) | 2 (9.5) | 0.097 |
| Rash | 7 (19.4) | 19 (52.8) | 10 (27.8) | 0.468 |
| Purpura | 14 (26.9) | 30 (57.7) | 8 (15.4) | 0.002 |
| Vomiting | 7 (17.9) | 20 (51.3) | 12 (30.8) | 0.340 |
| Nausea | 9 (19.1) | 25 (53.2) | 13 (27.7) | 0.270 |
| Joint pain | 16 (32.0) | 27 (54.0) | 7 (14.0) | 0.277 |
| Abdominal pain | 0 (0.0) | 24 (64.9) | 13 (35.1) | 0.0001 |
| Haemorrhagic manifestation* | 0 (0.0) | 8 (72.7) | 3 (27.3) | 0.083 |
| Respiratory difficulties | 1 (7.1) | 4 (28.6) | 9 (64.3) | 0.004 |
| Ascites | 0 (0.0) | 1 (12.5) | 7 (87.5) | 0.001 |
| Pleural effusion | 0 (0.0) | 2 (18.2) | 9 (81.8) | 0.0001 |
WBC = white blood cell; Hct = hematocrit test; PLT = platelets; DwoWS = dengue without warning signs; DwWS = dengue with warning signs; SD = severe dengue. Numbers in the parentheses indicate percentage, unless stated otherwise. All comparisons for categorical variables between/among the groups are performed by using the chi-square test or Fisher’s exact test as appropriate, whereas the comparison for continuous variables is performed by using the Kruskal–Wallis test (for more than two groups) and the Mann–Whitney U test (between two groups). P < 0.05 is considered significant.