Table 2.
Diagnostic profiles of children with different dengue severity grades in Vietnam, 2017
| Severity grades | |||||
|---|---|---|---|---|---|
| Laboratory diagnosis assays | Total | DwoWS | DwWS | SD | P-value |
| DENV NS1 Ag positive | 45 | 16 (35.6%) | 21 (46.7%) | 8 (17.8%) | 0.011 |
| Virus Isolation | |||||
| DENV-1 | 16 | 6 (37.5%) | 10 (62.5%) | 0 | 0.648 |
| Primary | 6 | 2 | 4 | 0 | |
| Secondary | 10 | 4 | 6 | 0 | |
| DENV-4 | 4 | 2 (50.0%) | 2 (50.0%) | 0 | – |
| Secondary | 4 | 2 | 2 | 0 | |
| DENV RNA detection* | |||||
| DENV-1 | 40 | 9 | 19 | 12 | 0.549 |
| DENV-2 | 3 | 2 | 0 | 1 | |
| DENV-3 | 1 | 0 | 1 | 0 | |
| DENV-4 | 18 | 4 | 8 | 6 | |
| DENV IgM positive | 76 | 19 | 36 | 21 | – |
| DENV IgG detection | |||||
| Primary | 21 | 5 (23.8%) | 12 (57.1%) | 4 (19.0%) | 0.540 |
| Secondary | 55 | 14 (25.5%) | 24 (43.6%) | 17 (30.9%) | – |
* DENV serotypes are detected by real-time RT-PCR. All comparisons for categorical variables between/among the groups are performed by using the chi-square test or Fisher’s exact test as appropriate, whereas the comparison for continuous variables is performed by using the Kruskal–Wallis test (for more than two groups) and the Mann–Whitney U test (between two groups). P < 0.05 is considered significant.