Table 1.

Performance characteristics for each malaria antigen assay used in the 5-Plex HRP2, Pf LDH for P. falciparum, Pv LDH for P. vivax, and Pan LDH for all malaria species

Analyte	Target polymerase chain reaction-confirmed infection	Threshold (pg/mL)	Sensitivity (95% CI)	Specificity (95% CI)
HRP2	P. falciparum	6.9	92.7 (86.6–96.6)	99.5 (97.2–100)
Pf LDH	P. falciparum	553.6	71.5 (62.7–79.3)	99.7 (98.3–100)
Pv LDH	P. vivax	314.8	46.1 (37.3–55.1)	99.7 (98.3–100)
Pan LDH	All malaria	49.0	83.8 (78.9–88.1)	99.5 (97.2–100.0)

HRP2 = histidine-rich protein 2; P. falciparum = Plasmodium falciparum; Pf LDH = P. falciparum-specific lactate dehydrogenase; Pv LDH = P. vivax–specific LDH; Pan LDH = Pan malaria lactate dehydrogenase.