Figure 1.

Endotoxin levels do not change after treatment, do not correlate with schistosome circulating anodic antigen (CAA) or stool eggs, and do not differ significantly by infection status over time. (A) For schistosome‐infected women who became negative at month 3 after treatment: comparison of endotoxin levels between baseline and month 3. (B) For all positive samples: plot of the data used for regression of endotoxin levels on log CAA; a linear regression model with cluster‐robust standard errors was used to account for within‐patient correlation across time points. Each dot represents a different set of measurements. (C) For participants positive for eggs: plot of the data used for regression of endotoxin levels on stool eggs/g (eggs were only found at baseline). (D) For all samples: comparison over time of plasma endotoxin levels between those with and without schistosome infections; schistosome infection status was reassigned at each time point. A linear mixed model, with time and schistosome infection fixed effects and patient-specific random effects, was used to account for within‐patient correlation across time.