Table 2.
Summary of main laboratory findings and treatment
| Subject | Met MoPH case definition | Yersinia pestis status | Reported antibiotics | Serum antibiotics | Bld and Spt cultures | White blood cell count (%Neu) | C-reactive protein (mg/L) | PCR Nas | ATB (days) | Outcome (day) | Final classification (MoPH) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Yes | NS and SC | Gent | Co-trim and cipro | − | 7.73 (86) | 134 | ADV | Gent (4) and cipro (10) | Alive (D12) | Confirmed |
| 2 | No | – | Co-trim | Co-trim | – | 9.23 (64) | 5 | ADV | Strepto (8) | Alive (D8) | Suspected |
| 3 | No | – | Co-trim, and gent | Co-trim | – | 4.81 (83) | 36 | ADV | Levoflo (10) | Alive (D9) | Suspected |
| 4 | No | – | None | None | – | 11,08 (68) | 5 | ADV | Strepto (8) | Alive (D8) | Suspected |
| 5 | No | – | None | None | – | 8.22 (67) | 41 | HRV | Strepto (8) | Alive (D8) | Suspected |
| 6 | No | – | Cipro | None | – | 13.7 (90) | 89 | ADV | Strepto (1)* | Alive (D5) | Suspected |
| 7 | No | RDT+ and IgG+ | Unknown med | Doxy | – | n/a | n/a | ADV/Sa | Levoflo (10)† | Alive (D14) | Probable |
| 8 | Yes | – | Co-trim | Co-trim | – | 11.9 (71) | 75 | HRV‡/Sp | Levoflo (7) | Alive (D8) | Suspected |
| 9 | No | – | None | Co-trim | – | 7.23 (71) | 5 | NL63/ADV | Strepto (8) | Alive (D8) | Suspected |
| 10 | Yes | RDT+, PCR+, and SC | None | None | Kp (Spt) | 34.74 (79) | 323 | HPEV | Gent (3) and levoflo (10) | Alive (D14) | Confirmed |
| 11 | No | NS and rest− | None | None | – | n/a | n/a | HRV/Sp | Strepto (1) and cipro (2)* | Alive (D2) | Suspected |
| 12 | No | – | None | None | – | 2.15 (60) | 158 | Influenza virus A‡/Sp | Gent (2), levoflo (2), and ceftri (6) | Alive (D8) | Suspected |
| 13 | No | NS and rest− | Gent | None | – | n/a | n/a | ADV‡/Sp | None | Alive (D2) | Suspected |
| 14 | No | RDT+ | Unknown med | None | – | 5.39 (62) | 16 | n/a | Levoflo (5) | Alive (D5) | Probable |
| 15 | Yes | – | None | Doxy | Sa (Bld) | n/a | n/a | NL63‡/Sa | Gent (4) and cipro (4) | Alive (D4)§ | Suspected |
| 16 | Yes | – | Unknown med | Cipro | – | n/a | n/a | n/a | Gent (1) | Died (D1) | Suspected |
| 17 | No | – | Cipro | None | – | 4.74 (38) | 5 | n/a | Strepto (8) | Alive (D8) | Suspected |
| 18 | No | – | None | Co-trim | Sp (Bld) | 11.75 (74) | 74 | n/a | Strepto (8) | Alive (D8) | Suspected |
| 19 | No | – | None | Co-trim and gent | – | 25.93 (87) | 129 | HPEV‡/Sp | Strepto (8) | Alive (D8) | Suspected |
| 20 | Yes | – | None | Co-trim | – | 25.37 (88) | 157 | ADV | Strepto (8) | Alive (D8) | Suspected |
ADV = adenovirus; ATB = antibiotics received during hospital admission (with duration in days); Bld = blood; Cipro = ciprofloxacin; Co-trim = co-trimoxazole; Doxy = serum antibiotics; Gent = gentamicin; HPEV = paraechovirus; HRV = rhinovirus; MoPH = Ministry of Public Health; n/a: not available; NL63 = coronavirus NL63; NS = no sputum; PCR Nas = polymerase chain reaction on nasopharyngeal swab; RDT = rapid diagnostic test; Spt = sputum; Unknown med = unknown medication; %Neu = percentage of neutrophils.
* Antibiotics discontinued.
† Antibiotic started 4 days after inclusion.
‡ Multiple viruses detected on PCR, only virus with the lowest cycle threshold is shown.
§ Self-discharge against medical advice (ciprofloxacin was continued after discharge).