Table 1:
Standard characteristics for nasal inhalation based on passive nasal inhalation and deep nasal inhalation.
| Description | Passive Nasal | Deep Nasal |
|---|---|---|
| VT (L) | 0.75 | 1.75 |
| breaths/min | 12 | 8 |
| I:E | 1:2 | 1:2 |
| Tinhale (s) | 1.67 | 2.5 |
| Ttotal (s) | 5.0 | 7.5 |
| Qmean (LPM) | 27.0 | 42.0 |
| Qmax (LPM) | 42.3 | 65.9 |
| t1a (s) | 0.14 | 0.135 |
| t2b (s) | 1.5 | 2.4 |
| t2-t1c (s) | 1.36 | 2.27 |
| ttransitd (s) | 0.2 | 0.2 |
| texite (s) | 0.5 | 0.5 |
a
Intersection of breathing flow and HFNC flow rate - falling pressure
b
Intersection of breathing flow and HFNC flow rate - rising pressure
c
Time that HFNC flow rate is below breathing flow rate
d
Transit time through the LV-DPI + LFNC system between the start of actuation and the first appearance of aerosol from the cannula tip.
e
Time for the aerosol to exit the LV-DPI and LFNC system from the first to the last appearance of powder from the cannula tip.