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. 2019 Jan 21;28(5):347–353. doi: 10.1097/PAI.0000000000000760

FIGURE 1.

FIGURE 1

Different IHC ER expression in serial sections of breast cancer as found in the NordiQC assessment scheme, run B15/2013. A, ER negative tumor. No nuclear staining reaction of the tumor cells was found in any of 225 submitted stains based on the mAb clone 1D5 or the rmAb clones EP1 and SP1. B, Same tumor area as in A showing diffuse, weak to moderate nuclear ER staining reaction, considered to be false positive, which was confirmed by ESR1 mRNA-ISH, score=0. This staining pattern was obtained in 15 of 37 submitted stains based on the mAb clone 6F11.