Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 23;40(6):1559–1573. doi: 10.1161/ATVBAHA.120.314297

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors.

Arteriosclerosis, Thrombosis, and Vascular Biology is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

PMC Copyright notice

Figure 6. — EP4 (prostaglandin E receptor 4) pathway induced IL (interleukin)-6 production and lysyl oxidase inhibition in human abdominal aortic aneurysm (AAA) vascular smooth muscle cells (VSMCs) and AAA tissues. A, IL-6 protein expression was measured by ELISA in human AAA (hAAA) VSMCs stimulated with the indicated drugs. n=5 to 8. B and C, Representative image and expression level of lysyl oxidase protein in supernatant of hAAA VSMCs stimulated with EP4 agonist. D, Elastica van Gieson–stained (EVG) and immunohistochemically stained sections of tissue from aorta and AAA. Scale bars=50 μm. E, Semiquantitative analysis of D in control aorta (hAorta) and hAAA. n=6 to 7. ND indicates not detected; and TAK1, transforming growth factor-β–activated kinase 1. *P<0.05, **P<0.01, ***P<0.001.