Table 2.
Univariable Factors Associated with Surgical Approach for Treating the Primary Site of Acral Lentiginous Melanoma
| Digital Amputation | Partial Digital Amputation | Wide Local Excision | P | ||
|---|---|---|---|---|---|
| n | 12 | 9 | 22 | ||
| Age (median, years) | 60 [IQR: 56, 76.5] | 61 [IQR: 55, 78] | 58 [IQR: 49, 67] | 0.28 | |
| Gender | Male | 7 (58%) | 4 (44%) | 10 (45%) | 0.74 |
| Female | 5 (42%) | 5 (56%) | 12 (55%) | ||
| Thickness (median, mm) | 3.6 [IQR: 1.1, 5] | 4.5 [IQR: 2.5, 5] | 2.4 [IQR: 1.1, 4.3] | 0.62 | |
| Hand or foot | Hand | 3 (25%) | 6 (67%) | 3 (14%) | 0.01 |
| Foot | 9 (75%) | 3 (33%) | 19 (86%) | ||
| Subungual location | Subungual | 7 (78%) | 8 (89%) | 4 (22%) | <0.001 |
| Nonsubungual | 2 (22%) | 1 (11%) | 14 (78%) | ||
| Clark level | <V | 6 (60%) | 4 (57%) | 14 (82%) | 0.32 |
| V | 4 (40%) | 3 (43%) | 8 (53%) | ||
| Ulceration | Yes | 6 (55%) | 4 (57%) | 7 (47%) | 0.87 |
| No | 5 (45%) | 3 (43%) | 8 (53%) | ||
| Mitotic rate (per mm2) |
>3 | 5 (71%) | 2 (50%) | 2 (20%) | 0.1 |
| ≤3 | 2 (29%) | 2 (50%) | 8 (80%) |
IQR, interquartile range.