Fig. 1.

Clinical manifestations of RT x-induced soft tissue injury. Clinical photographs demonstrating the spectrum of complications resulting from RT x-induced soft tissue injury to normal tissues. A, Adjuvant RT x for control of lymph node involvement of cancers from the breast or chest wall resulting in severe scarring, telangiectasia skin change and fibrosis, which can significantly impair the mobility of soft tissue the upper limb due to axillary contractures. B, The integrity and compliance of irradiated tissues is compromised, resulting in wound break down and exposure of underlying structures such as bone or metal reconstruction plates. C, Demonstrates significant issues with wound healing, even in situations where healthy, un-irradiated tissue (flap) has been transferred from a distant site of the body to the irradiated field.