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. 2020 Mar 27;8(3):e2723. doi: 10.1097/GOX.0000000000002723

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Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Fig. 2. — Microscopic observation of changes in collagen density on days 3 and 8 after injection. Increases in the density of the collagen network are observed following VYC-12L and HYD treatment in the papillary and upper reticular dermis by the heightened intensity of green staining as compared with control. Improvements in the relief of the dermal–epidermal junction may be seen with VYC-12L (arrow). HYD, noncrosslinked hyaluronic acid with mannitol; VYC-12L, crosslinked hyaluronic acid injectable gel with lidocaine.