TABLE 4.
Resistome and mobilome characteristics of the isolates
| Plasmid type and sample code (MLST clone) | Species | Resistance genes | Plasmid replicons | pMLST | Integron(s) |
|---|---|---|---|---|---|
| IncF[F-:A13:B-] | |||||
| EC009 (ST-231) | Enterobacter hormaechei | arr-2::ere(A), aac(3)-IIa, aadA1, strA::strB::sul2, fosA, oqxA::oqxB, sul1::cmlA1, dfrA14, catA2, blaACT-25, catB3::blaOXA-1::aac(6')Ib-cr5, blaTEM-1B::blaCTX-M-15, blaOXA-9, aph(3'')-Ib, aph(6)-Id, blaLAP-2, catA, cmlA5, qacEΔ1, qnrS1 | IncR, ColpVC, ColRNAI | IncF[F-:A13:B-] | In191 |
| EC010 (ST-231) | Enterobacter hormaechei | aph(3'')-Ib, aph(6)-Id, aadA1, aac(3)-IIa, qnrS1, qnrB1, fosA, sul1, dfrA14, dfrA1, tet(A), tet(B), blaACT-41::IS2::qnrS1, sul2::strB::strA::blaTEM-1B::blaCTX-M-15, blaCMY/LAP-2, aac(6')Ib-cr5::blaOXA-1:catB3, oqxA::oqxB, catA, qacEΔ1, tet(A) | Col(BS512), IncR, Col(MG828), ColpVC, ColRNAI | IncF[F-:A13:B-] | In191 |
| CF003 | Citrobacter freundii | blaCMY-79, aac(6')-If | IncA/C2, ColRNAI | IncHI2[ST-1], IncF[F-:A13*:B-] | None |
| IncHI2[ST-1] | |||||
| CF003 | Citrobacter freundii | blaCMY-79, aac(6')-If | IncA/C2, ColRNAI | IncHI2[ST-1], IncF[F-:A13*:B-] | None |
| EC001 (ST-459) | Enterobacter hormaechei | arr-2::ere(A), aadA24, aac(3)-IIa, strA::strB::sul2, sul1::cmlA1, qnrS1, fosA, oqxA::oqxB, dfrA14, catB3, blaOXA-1::aac(6')Ib-cr, catA2, blaACT-7, blaOXA-9, blaTEM-1B::blaCTX-M-15 | IncR, ColRNAI | IncHI2[ST-1] | In191, In705, In363 |
| EC015 | Enterobacter hormaechei | aadA1, strB, strA, aac(3)-IIa, sul2, fosA, qnrB1, dfrA14, tet(A), catA1, catB3, blaACT-16, blaCTX-M-15, blaOXA-1, blaTEM-1B, aac(6')Ib-cr | ColRNAI | IncHI2[ST-1] | In191, In705 |
| K006 | Enterobacter hormaechei | aac(3)-II, aac(6')-IIc, aac(6')-Ib3, aadA2, aph(3'')-Ib, aph(3')-Ia, aph(6)-Id, arr, blaACT-56, blaSHV-12, blaTEM-1, catA, catA2, dfrA19, ere(A), fosA, mcr-9.1, qacEΔ1, sul1, sul2, tet(D) | ColRNAI | IncHI2[ST-1], IncF[K1:A-:B-] | In46, In127, In615 |
| K130 (ST-90) | Enterobacter hormaechei | aacA4, aadA2, strA, aph(3')-Ia, aac(6')-IIc, strB, fosA, ere(A), sul1, sul2, tet(D), catA2, blaTEM-1B, blaACT-15, aac(6')Ib-cr, aac(3)-II, aac(6')-Ib3, aph(3'')-Ib, aph(3')-Ia, aph(6)-Id, arr, blaACT-56, blaSHV-12, catA, dfrA19, mcr-9.1, qacEΔ1 | ColRNAI | IncHI2[ST-1] | In127, In46, In615 |
| K063 | Enterobacter hormaechei | aacA4, aadA2, aac(3)-IIa, aph(3')-Ia, aadA1, sul1, sul2, fosA, ere(A), qnrA1, dfrA12, dfrA19, tet(D), catB3, catA2, blaACT-15, blaTEM-1A, blaCTX-M-15, blaOXA-1, blaOXA-9, aac(6')-IIc, aac(6')-Ib3, aph(3'')-Ib, aph(6)-Id, arr, blaACT-56, blaSHV-12, mcr-9.1, qacEΔ1 | IncR, ColRNAI | IncF[K2:A13:B-], IncHI2[ST-1] | In127, In46, In615 |
| IncF[K12:A-:B-] | |||||
| K001 (ST-1791) | Klebsiella variicola | arr-3, fosA, sul2, aacA4, strB, strA, qnrB66, oqxB, oqxA, frA14, blaCTX-M-15, blaLEN13, blaTEM-1B, aac(6')Ib-cr | IncR, ColRNAI | IncF[K12:A-:B-] | In191, In792 |
| IncF[K1:A-:B-] | |||||
| K006 | Enterobacter hormaechei | aac(3)-II, aac(6')-IIc, aac(6')-Ib3, aadA2, aph(3'')-Ib, aph(3')-Ia, aph(6′*)-Id, arr, blaACT-56, blaSHV-12, blaTEM-1, catA, catA2, dfrA19, ere(A), fosA, mcr-9.1, qacEΔ1, sul1, sul2, tet(D) | ColRNAI | IncHI2[ST-1], IncF[K1:A-:B-] | In46, In127, In615 |
| IncF[K2:A13:B-] | |||||
| K063 | Enterobacter hormaechei | aacA4, aadA2, aac(3)-IIa, aph(3')-Ia, aadA1, sul1, sul2, fosA, ere(A), qnrA1, dfrA12, dfrA19, tet(D), catB3, catA2, blaACT-15, blaTEM-1A, blaCTX-M-15, blaOXA-1, blaOXA-9, aac(6')-IIc, aac(6')-Ib3, aph(3'')-Ib, aph(6)-Id, arr, blaACT-56, blaSHV-12, mcr-9.1, qacEΔ1 | IncR, ColRNAI | IncF[K2:A13:B-], IncHI2[ST-1] | In127, In46, In615 |
| pMLST not detected | |||||
| PM005 | Providencia alcalifaciens | aac(3)-IIa, aadA2, sul2, sul1, dfrA12, tet(J), tet(A), cat, floR, aph(3'')-Ib, aph(6)-Id, blaCMY-2, blaSCO-1, blaTEM-131, catA, qacEΔ1 | A/C2 | None | In27 |
| CF004 | Citrobacter freundii | blaCMY-151, fosA7 | None | None | None |