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. 2020 Mar 10;28(6):763–769. doi: 10.1038/s41431-020-0600-5

Fig. 1. Illustration of the Camta1 protein.

Fig. 1

The full-length Camta1 protein consists of 1673 amino acids and contains a CG1 DNA-binding domain (position 67–183), transcription factor immunoglobulin-like DNA-binding domain (TIG) domain (position 873–952), Ankyrin repeats for oligomerization (positions 1064–1086; 1109–1129; 1143–1172), and IQ motifs involved in calmodulin binding (positions 1547–1576; 1577–1599; 1600–1622). Arrows indicate where the patient variants are located. Bars below the image indicate the locations of CNVs as described by Thevenon et al. [9] and Shinawi et al. [10]. Exons are numbered as in NG_053148.1.