Table 1.
Summary table of transplantation outcomes with oviductal and OSE organoids.
| Origin | Clone | No. of injected cells | Orthotopic tumor take | Subcutaneous tumor take |
|---|---|---|---|---|
| Oviduct | WT | ca 100,000 | 0/6 (0%) | 0/2 (0%) |
| OSE | WT | ca 100,000 | 0/6 (0%) | 0/2 (0%) |
| Oviduct | T | ca 100,000 | 0/8 (0%) | 0/4 (0%) |
| OSE | T | ca 100,000 | 0/8 (0%) | 0/4 (0%) |
| Oviduct | TB | ca 100,000 | 0/8 (0%) | 2/4 (50%) |
| OSE | TB | ca 100,000 | 0/6 (0%) | 0/4 (0%) |
| Oviduct | TBN | ca 100,000 | 11/12 (92%) | 6/6 (100%) |
| OSE | TBN | ca 100,000 | 0/8 (0%) | 5/8 (63%) |
| Oviduct | TBP | ca 100,000 | 12/12 (100%) | 6/6 (100%) |
| OSE | TBP | ca 100,000 | 0/8 (0%) | 2/4 (50%) |
OSE—ovarian surface epithelium, WT—wild type, T—Trp53 mutant, TB—Trp53, Brca1 mutant, TBN—Trp53, Brca1, Nf1 mutant, TBP—Trp53, Brca1, Pten mutant.