Binding/release assays for various materials loaded with BMP-2. Data represent cumulative rhBMP-2 release into surrounding media, where a flat slope represents no release. Reprinted with permission from Hsu EL et al. [14]. (Mary Ann Liebert, Inc., New Rochelle, NY, USA). rhBMP-2 recombinant human bone morphogenetic protein-2, ACS absorbable collagen sponge.