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Effect of aerobic training on maximal oxygen uptake and maximal workload in four patients with mtDNA mutation and one healthy subject. Maximal oxygen uptake (A) and maximal workload (B) before training and after 6 and 12 months of training in four patients with different mtDNA mutations (blue bars) and one healthy subject (yellow bar). *Different compared to before training (p < 0.05). #Different compared to before training and after 6 months of training.
