Element	Example
molecular modulators are trait factors	For example, γ-aminobutyric acid-A/benzodiazepine system
with conserved teleonomic purpose	For example, ensuring safe approach despite threat
which permits approximate lexical labelling	For example, “trait anxiety”
linked to hierarchical systems/subsystems	For example, GIS
with identifiable functions	For example, goal-conflict resolution
and extreme values leading to dysfunction	For example, “anxiety” disorder