Table 4.
Results of secondary tests of sex-by-disposition interactions in regressions of fractional anisotropy in 15 separate skeletonized white matter tracts at 22–31 years of age on ratings of negative emotionality, prosociality, and daring measured at 10–17 years of age controlling the other dispositions and demographic covariates of no interest,a separately by informant on the dispositions (N = 410)
| CADS informant: | Parent | Youth | |||
|---|---|---|---|---|---|
| Outcome | β (SE) | P < | B (SE) | P < | β (SE) |
| Corpus callosum (body) | NE | 0.14 (0.19) | 0.4663 | −0.53 (0.14) | 0.0002 |
| Prosociality | 0.33 (0.17) | 0.0584 | 0.02 (0.15) | 0.8902 | |
| Daring | 0.17 (0.12) | 0.1584 | −0.06 (0.13) | 0.6583 | |
| Corpus callosum (genu) | NE | 0.24 (0.17) | 0.1540 | −0.29 (0.10) | 0.0041 |
| Prosociality | 0.28 (0.20) | 0.1770 | −0.24 (0.12) | 0.0475 | |
| Daring | 0.21 (0.14) | 0.1349 | 0.03 (0.13) | 0.7989 | |
| Corpus callosum (splenium) | NE | 0.27 (0.13) | 0.0397 | −0.22 (0.12) | 0.0658 |
| Prosociality | 0.12 (0.14) | 0.3893 | −0.04 (0.14) | 0.7718 | |
| Daring | 0.05 (0.12) | 0.6721 | 0.10 (0.12) | 0.3969 | |
| Anterior corona radiata | NE | 0.18 (0.14) | 0.1853 | −0.07 (0.10) | 0.4813 |
| Prosociality | 0.23 (0.17) | 0.1804 | −0.13 (0.13) | 0.3417 | |
| Daring | 0.19 (0.12) | 0.1365 | 0.16 (0.16) | 0.3370 | |
| Superior corona radiata | NE | 0.11 (0.14) | 0.4002 | −0.27 (0.11) | 0.0173 |
| Prosociality | 0.35 (0.17) | 0.0372 | −0.17 (0.14) | 0.2194 | |
| Daring | 0.31 (0.10) | 0.0013 | 0.21 (0.11) | 0.0655 | |
| Posterior corona radiata | NE | −0.04 (0.14) | 0.7881 | −0.40 (0.11) | 0.0003 |
| Prosociality | 0.35 (0.15) | 0.0220 | −0.17 (0.12) | 0.1648 | |
| Daring | 0.29 (0.14) | 0.0339 | 0.18 (0.10) | 0.0833 | |
| Internal capsule | NE | 0.13 (0.14) | 0.3443 | −0.11 (0.09) | 0.2122 |
| Prosociality | 0.32 (0.16) | 0.0502 | −0.06 (0.12) | 0.5830 | |
| Daring | 0.20 (0.10) | 0.0536 | 0.18 (0.13) | 0.1608 | |
| External capsule | NE | 0.16 (0.15) | 0.2714 | −0.42 (0.15) | 0.0053 |
| Prosociality | 0.22 (0.16) | 0.1730 | 0.02 (0.14) | 0.8735 | |
| Daring | −0.04 (0.19) | 0.8572 | 0.15 (0.14) | 0.2985 | |
| Cingulum | NE | 0.22 (0.14) | 0.1139 | −0.26 (0.08) | 0.0028 |
| Prosociality | 0.34 (0.17) | 0.0473 | −0.01 (0.15) | 0.9600 | |
| Daring | 0.14 (0.12) | 0.2475 | 0.13 (0.15) | 0.3874 | |
| Posterior thalamic radiation | NE | 0.22 (0.15) | 0.1513 | −0.26 (0.17) | 0.1215 |
| Prosociality | 0.09 (0.16) | 0.5876 | −0.24 (0.14) | 0.0841 | |
| Daring | 0.07 (0.15) | 0.6360 | 0.26 (0.13) | 0.0451 | |
| Uncinate fasciculus | NE | 0.01 (0.11) | 0.9082 | −0.14 (0.10) | 0.1600 |
| Prosociality | 0.01 (0.14) | 0.9315 | −0.04 (0.16) | 0.8069 | |
| Daring | 0.11 (0.14) | 0.4409 | 0.14 (0.13) | 0.2564 | |
| Fornix | NE | 0.16 (0.13) | 0.2215 | −0.13 (0.10) | 0.1758 |
| Prosociality | 0.11 (0.15) | 0.4432 | −0.03 (0.16) | 0.8526 | |
| Daring | 0.03 (0.14) | 0.8001 | 0.00 (0.14) | 0.9741 | |
| Superior Fronto-Occ Fasciculus | NE | 0.26 (0.15) | 0.0939 | −0.14 (0.11) | 0.2120 |
| Prosociality | 0.49 (0.15) | 0.0019 | 0.03 (0.17) | 0.8643 | |
| Daring | 0.20 (0.12) | 0.0875 | 0.14 (0.14) | 0.3183 | |
| Superior longitudinal fasciculus | NE | 0.09 (0.12) | 0.4290 | −0.25 (0.10) | 0.0124 |
| Prosociality | 0.17 (0.14) | 0.2044 | −0.19 (0.15) | 0.2094 | |
| Daring | 0.34 (0.12) | 0.0065 | 0.36 (0.13) | 0.0066 | |
| Sagittal stratum | NE | 0.18 (0.17) | 0.2851 | −0.28 (0.20) | 0.1643 |
| Prosociality | 0.13 (0.16) | 0.4291 | −0.24 (0.12) | 0.0466 | |
| Daring | 0.09 (0.13) | 0.4868 | 0.14 (0.12) | 0.2543 |
Covariates of no interest: Age in Wave 1, age in Wave 2, parent-classified race-ethnicity (Non-Hispanic white versus others), handedness, scanner, and total intracranial volume.
Note: NE = negative emotionality; Occ = occipital; CADS scores and white matter tracts converted to z-scores.
Bold indicates significant after 5% false discovery rate correction for 90 tests of sex-by-disposition interactions for specific tracts.