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. 2020 May 21;10:748. doi: 10.3389/fonc.2020.00748

Figure 8.

Figure 8

CD11b modulation changes macrophage gene expression to enhance anti-tumor immunity. (A) Relative mRNA expression analysis of BMDMs treated with LLC TCM or TCM+GB1275 (20 μM) for 4 h in media containing M-CSF. Changes in gene expression are reported as relative mRNA expression from TCM (n = 3–6). (B) Q-PCR mRNA expression analysis of BMDMs from WT or CD11b KI mice treated with LLC TCM for 4 h in media containing M-CSF. Changes in gene expression are reported as relative mRNA expression from WT TCM (n = 3–6). *P < 0.05, **P < 0.01. Statistical analysis by student's t-test.