Figure 2.

A. Representative bars of quantitative analysis of the necrotic cells of the hilus area. Apigenin significantly ameliorated the necrotic effect of Amyloid Beta (Aβ) in hilus (P<0.001 compared with Aβ group).

Values are presented as Mean±SE (n=4).

^*** P<0.001 and ^** P<0.01 vs. control group; ^### P<0.001 vs. Aβ group.

B. a. Representative photomicrographs of Nissl-stained brain sections of the hilus area of the control; b. Apigenin; C. Amyloid beta (Aβ); and D. Aβ+apigenin groups.

The lower magnification is presented above. Severe cell loss is evident in the Aβ group (arrow), which remarkably conserved after apigenin treatment.

Scale bar for A–D: 50 μm (n=4).