Table 1.
Comparison of baseline clinical and demographic variables among patients with vascular and nonvascular etiology
| Vascular | Nonvascular | Significance | |
|---|---|---|---|
| Number of patients | 72 | 17 | |
| Age, years | 65.6±14.8 | 55.7±17 | 0.018a |
| Male sex | 52.8% | 41.1% | 0.39b |
| Median admission NIHSS score | 15.5 (9–20) | 11 (7.5–15.5) | 0.171c |
| Hypertension | 80.5% | 76.5% | 0.741d |
| Admission systolic BP, mm Hg | 155±30 | 159±38 | 0.654a |
| Admission diastolic BP, mm Hg | 89±18 | 98±25 | 0.09a |
| Diabetes mellitus | 37.5% | 35.2% | 0.866b |
| Admission glucose level, mg/dL | 137±62 | 129.6±60 | 0.658a |
| Hyperlipidemia | 62.5% | 47% | 0.243b |
| LDL, mg/dL | 104±41 | 90±35 | 0.251a |
| HDL, mg/dL | 44.7±18 | 43.3±14 | 0.799a |
| Triglyceride, mg/dL | 128.8±76 | 94±31 | 0.109a |
| Cholesterol, mg/dL | 173.9±47.8 | 152±38 | 0.127a |
| Coronary artery disease | 15.3% | 23.5% | 0.474d |
| Congestive heart failuree | 19.4% | 5.9% | 0.285d |
| Atrial fibrillation | 30.5% | 5.9% | 0.061d |
| Intravenous tPA rate | 38.9% | 0% | 0.002b |
| Time from stroke onset to MRI, min | 318±151 | 267.6±100 | 0.197a |
| MRI turnaround time, min | 92±45 | 108.6±60 | 0.218a |
| Mortality | 9.7% | 0% | 0.338d |
| Mismatch | 35 (48.6%) | 0 | 0.000b |
| Vessel occlusion | 39 (54.2%)f | 0 | 0.000b |
| Perfusion-diffusion mismatch | 70.8% | 58.8% | 0.337b |
| Clinical diffusion mismatch | 29.2% | 41.2% | |
| Endovascular therapy | 34.7% | 0% | 0.002d |
BP, blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NIHSS, National Institutes of Health Stroke Scale; tPA, tissue plasminogen activator.
a
Student t test.
b
χ2 test.
c
Mann-Whitney U test.
d
Fisher exact test.
e
Ejection fraction ≤45%.
f
One patient had severe stenosis of >99% measured by cerebral angiography.