Table 3.
Comparison of baseline clinical and demographic variables between subgroups with and without mismatch in AIS patients with vessel occlusion
| Mismatch | No mismatch | Significance | |
|---|---|---|---|
| Number of patients | 32 | 7 | |
| Age, years | 64.4+15.6 | 76.7±7.2 | 0.0495a |
| Male sex | 56% | 28.5% | 0.235c |
| Median admission NIHSS score | 17.5 (12–21) | 19 (16–22) | 0.474b |
| Hypertension | 78% | 100% | 0.313c |
| Admission systolic BP, mm Hg | 158±30 | 150±19 | 0.529a |
| Admission diastolic BP, mm Hg | 89.5±14 | 91±19 | 0.813a |
| Diabetes mellitus | 31% | 57% | 0.225c |
| Admission glucose level, mg/dL | 138±47 | 114±21 | 0.201a |
| Hyperlipidemia | 57% | 71% | 0.438c |
| LDL, mg/dL | 95.7±34.4 | 125±40 | 0.071a |
| HDL, mg/dL | 40.3±12 | 46±16 | 0.33a |
| Triglyceride, mg/dL | 100.3±45 | 126.8±35.5 | 0.182a |
| Cholesterol, mg/dL | 156±40 | 196±48 | 0.035a |
| Coronary artery disease | 19% | 28.6% | 0.617c |
| Congestive heart failure | 22% | 71.4% | 0.02c |
| Atrial fibrillation | 43.8% | 14.3% | 0.216c |
| Time from stroke onset to MRI, min | 290±141 | 300±147 | 0.877a |
| MRI turnaround time, min | 92±33 | 87±38 | 0.758a |
| Mortality | 15.6% | 28.6% | 0.588c |
| Perfusion-diffusion mismatch | 84% | 57% | 0.137c |
| Clinical diffusion mismatch | 16% | 43% | |
| DWI lesion volume | |||
| None to small | 20 (62.5%) | 1 (14.3%) | |
| Medium to large | 12 (37.5%) | 6 (85.7%) | 0.038c |
| Vessel occlusion site | |||
| Anterior | 31 (96.8%) | 5 (71%) | 0.077c |
| Posterior | 1 (3.2%) | 2 (2.9%) |
AIS, acute ischemic stroke; BP, blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NIHSS, National Institutes of Health Stroke Scale.
a
Student t test.
b
Mann-Whitney U test.
c
Fisher exact test.