Fig. 13.

Photomicrographs of liver section from rats treated with (A) Normal saline (control) showing normal hepatic architecture with central vain (CV), surrounding hepatocytes (H) and array of radiating sinusoids (S) (scored as 0). (B) 50 mg/kg of lead (LTG) showing congestion of central vain (arrow), fatty changes, foci of hepatic necrosis (N), pyknotic nuclei, infiltration of inflammatory cells (star) and numerous activated kupffer cells (AKC) (scored as 3). (H and E, X 10, scale bar = 200 µm).