Table 3.
Pathological parameters | Control | LTG | Mann Whitney U test (p < value) |
---|---|---|---|
Activated Kupffer cells | 0.4 ± 0.24 | 2.3 ± 0.2* | 0.0079 |
Sign of necrosis | 0.2 ± 0.2 | 2.5 ± 0.16* | 0.0079 |
Vacuolation (fatty changes) | 0.2 ± 0.2 | 2.6 ± 0.19* | 0.0079 |
Inflammatory cell infiltration | 0.2 ± 0.2 | 2.3 ± 0.26* | 0.0079 |
Karyolysis | 0.2 ± 0.2 | 2.3 ± 0.13* | 0.0079 |
Pyknosis | 0.2 ± 0.2 | 2.5 ± 0.16* | 0.0079 |
Karyorrhexis | 0.0 | 0.6 ± 0.24* | 0.1667 |
The symbol * denotes the values were significantly different (p < 0.05) between lead-administered and the control groups of rats. Values were presented as mean ± SEM, n = 5.