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. 2020 May;65:1–9. doi: 10.1016/j.biologicals.2020.02.005

Table 3.

Blockbustera products in the USA [14].

Brand name Indication Global sales in 2017 International Nonproprietary Name
Humira Rheumatoid arthritis, plaque psoriasis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, polyarticular juvenile idiopathic arthritis $18.4 billion Adalimumab
Rituxan Non-Hodgkins lymphoma, chronic lymphocytic leukaemia, rheumatoid arthritis $9.2 billion Rituximab
Enbrel Rheumatoid arthritis, plaque psoriasis, psoriatic arthritis $7.9 billion Etanercept
Herceptin HER2+ breast cancer $7.4 billion Trastuzumab
Avastin Breast, colorectal, kidney, non-small-cell lung, glioblastoma, ovarian cancers $7.1 billion Bevacizumab
Remicade Rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, ulcerative colitis $7.1 billion Infliximab
Lantus Diabetes $5.7 billion Insulin glargine
Neulasta Cancer chemotherapy $4.7 billion Pegfilgrastim
Avonex Multiple sclerosis $2.1 billion Interferon beta-1a
Lucentis Age-related macular degeneration $1.5 billion Ranibizumab

HER2: human epidermal growth factor receptor 2.

a

Blockbusters are defined here as products with annual sales of more than $1 billion.