Table 1.
Demographic and clinical data in NMO, RRMS, and HC groups.
| NMO | RRMS | HC | p | |
|---|---|---|---|---|
| No. of subjects | 20 | 40 | 20 | — |
| Gender (male) | 4 (20%) | 8 (20%) | 4 (20%) | 1.0 |
| Age (years) | 48 ± 10 | 47 ± 9 | 50 ± 8 | 0.54 |
| Disease duration (years) | 11.4 ± 8.7 | 14.1 ± 8.2 | — | 0.25 |
| EDSS (points) | 4.5 ± 1.2a | 3.1 ± 1.6a | 0.0 ± 0.0a | <0.0001 |
| Annual relapse rate | 0.5 (0-3)b | 0.0 (0-2)b | 0.058 |
aAll between-group difference significant (pairwise comparison), bmedian (range). Abbreviations: NMO: neuromyelitis optica; RRMS: remittent-relapsing multiple sclerosis; HC: healthy controls; EDSS: expanded disability status scale. Unless otherwise indicated, data are presented as mean ± standard deviation.