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. 2020 Apr 6;4(1):e000635. doi: 10.1136/bmjpo-2020-000635

Table 4.

Multivariable logistic regression model for the association between maternal ethnicity and iron deficiency and iron deficiency anaemia

Variable Iron deficiency (ID) Iron deficiency Anaemia (IDA)
ß (95% CI) OR (95% CI) P value ß (95% CI) OR (95% CI) P value
Maternal ethnicity
 European Referent Referent
 East Asian −1.013 (−1.947 to −0.079) 0.36 (0.14 to 0.92) 0.03* −1.025 (−3.039 to 0.989) 0.36 (0.05 to 2.69) 0.32
 Southeast Asian −0.355 (−1.337 to 0.627) 0.70 (0.26 to 1.87) 0.48 −0.658 (−2.708 to 1.392) 0.52 (0.07 to 4.02) 0.53
 South Asian 0.518 (0.043 to 0.993) 1.68 (1.04 to 2.70) 0.03* 0.190 (−0.661 to 1.040) 1.21 (0.52 to 2.83) 0.66
 West Asian/North African 0.876 (0.031 to 1.722) 2.40 (1.03 to 5.60) 0.04* −0.707 (−2.817 to 1.404) 0.49 (0.06 to 4.07) 0.51
 African and Caribbean −0.515 (−1.397 to 0.367) 0.60 (0.25 to 1.44) 0.25 0.246 (−0.875 to 1.367) 1.28 (0.42 to 3.92) 0.67
 Latin American −0.244 (−1.100 to 0.612) 0.78 (0.33 to 1.85) 0.57 −0.230 (−1.759 to 1.300) 0.79 (0.17 to 3.67) 0.77
 Indigenous 0.502 (−1.885 to 2.890) 1.65 (0.15 to 17.99) 0.68 1.745 (−0.832 to 4.322) 5.73 (0.44 to 75.37) 0.18
 Mixed 0.455 (−0.107 to 1.018) 1.58 (0.90 to 2.77) 0.11 0.757 (−0.084 to 1.597) 2.13 (0.92 to 4.94) 0.08
Child sex
 Male Referent Referent
 Female −0.129 (−0.427 to 0.169) 0.88 (0.65 to 1.18) 0.40 −0.216 (−0.737 to 0.305) 0.81 (0.48 to 1.36) 0.42
Child's age, months†
 12–15 0.215 (0.005 to 0.425) 1.24 (1.01 to 1.53) 0.04* 0.274 (−0.057 to 0.605) 1.31 (0.94 to 1.83) 0.10
 15–18 −0.078 (−0.257 to 0.101) 0.92 (0.77 to 1.11) 0.39 −0.292 (−0.588 to 0.004) 0.75 (0.56 to 1.00) 0.05
 18–24 −0.009 (−0.083 to 0.065) 0.99 (0.92 to 1.07) 0.81 −0.003 (−0.135 to 0.129) 1.00 (0.87 to 1.14) 0.97
 24–38 −0.111 (−0.158 to -0.066) 0.89 (0.85 to 0.94) <0.0001* −0.206 (−0.344 to −0.068) 0.81 (0.71 to 0.93) 0.003*
CRP level, mg/L −0.387 (−0.597 to −0.177) 0.68 (0.55 to 0.84) 0.0003* −0.114 (−0.353 to 0.125) 0.89 (0.70 to 1.13) 0.35
zBMI 0.126 (−0.020 to 0.271) 1.13 (0.98 to 1.31) 0.09 0.086 (−0.172 to 0.343) 1.09 (0.84 to 1.41) 0.51
Birth weight, kg
 ≥2.5 Referent Referent
 <2.5 0.266 (−0.222 to 0.754) 1.31 (0.80 to 2.13) 0.28 −0.361 (−1.365 to 0.643) 0.70 (0.26 to 1.90) 0.48
Maternal education
 Post-Secondary Referent Referent
 No post-secondary 0.174 (−0.402 to 0.751) 1.19 (0.67 to 2.12) 0.55 1.204 (0.415 to 1.992) 3.33 (1.51 to 7.33) 0.003*
Family income (CAN $)
 $80 000+ Referent Referent
 $30 000–$79 999 −0.305 (−0.763 to 0.152) 0.74 (0.47 to 1.16) 0.19 −0.425 (−1.249 to 0.399) 0.65 (0.29 to 1.49) 0.31
 Less than $30 000 0.647 (0.032 to 1.261) 1.91 (1.03 to 3.53) 0.04* 0.552 (−0.368 to 1.471) 1.74 (0.69 to 4.36) 0.24
Breastfeeding Duration, months‡ 0.051 (0.025 to 0.076) 1.05 (1.03 to 1.08) 0.0001* 0.057 (0.008 to 0.105) 1.06 (1.01 to 1.11) 0.02†
Bottle Use >15 months
 No Referent Referent
 Yes 0.099 (−0.280 to 0.478) 1.10 (0.76 to 1.61) 0.61 0.437 (−0.251 to 1.125) 1.55 (0.78 to 3.08) 0.21
Current infant formula use
 No Referent Referent
 Yes −2.256 (−3.303 to −1.209) 0.10 (0.04 to 0.30) <0.0001† −1.949 (−3.418 to −0.480) 0.14 (0.03 to 0.62) 0.009*
Cow's milk consumption
 Two cups (500 mL) or less Referent Referent
 More than two cups (500 mL) 0.474 (0.153 to 0.795) 1.61 (1.17 to 2.21) 0.004* −0.084 (−0.676 to 0.508) 0.92 (0.51 to 1.66) 0.78

All models adjusted for age, sex, zBMI, birth weight, maternal education, family income, CRP, breastfeeding duration (continuous variable), cow’s milk >2 cups, bottle use >15 months, infant formula use (Y/N).

*Statistically significant findings at p<0.05.

†Restricted cubic spline (RCS) analysis was used for child age.

‡Breastfeeding duration was included in model as a continuous variable.

CRP, C reactive protein; zBMI, body mass index z score.