Table 1.
Clinicopathological features of 80 high-grade serous ovarian carcinomas
Patient characteristics | All patients (n). | HR-deficient (n). (%) | HR-proficient (n). (%) | P value | |
80 | 34 | 46 | |||
Age | ≥55 | 52 | 17 (50) | 35 (76) | 0.0192 |
<55 | 28 | 17 (50) | 11 (24) | ||
Stage | I | 3 | 0 (0) | 3 (7) | 0.165 |
II | 7 | 2 (6) | 5 (11) | ||
III | 50 | 20 (59) | 30 (65) | ||
IV | 20 | 12 (35) | 8 (17) | ||
Residual tumor | Yes | 63 | 27 (79) | 36 (78) | 1 |
No | 17 | 7 (21) | 10 (22) | ||
Platinum-sensitivity* | Sensitive | 30 | 19 (60) | 11 (31) | 0.0039 |
Partial sensitive | 16 | 8 (25) | 8 (22) | ||
Resistant | 19 | 3 (9) | 16 (44) |
*The patients who refused or dropped out of chemotherapy (n=3) and who had no disease progression (n=12) were excluded.
†Significant values are underlined.
HR, homologous recombination.