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. Author manuscript; available in PMC: 2021 May 21.
Published in final edited form as: J Theor Biol. 2020 Feb 28;493:110222. doi: 10.1016/j.jtbi.2020.110222

Fig. 8.

Fig. 8.

Modeling ferroptosis sensitivity in FT-t cells. Ovarian cancer stem cell line FT-t has low p53, high TFRC, and low Fptn. We consider the sensitivity of FT-t cells to erastin under varying SCD and ACSL4. The relationship between conditions experimentally tested and modeled is shown on the right-hand side. For example, the first row shows input conditions identical to the control FT-t row, except the input parameter SCD1 is set to low, which corresponds to a knock down of SCD1 in FT-t cells.