Table 3.
Summary of articles addressing factors associated with cognitive outcomes after epilepsy surgery for low-grade epilepsy-associated neuroepithelial tumors
| Study | No. of patients | Parameters | Value | Factors associated with poor cognitive outcome |
|---|---|---|---|---|
| Faramand et al. (2018) [15] | 22 | Postoperative FSIQ | Seizure-free (n=14): 92.4 (range, 73–116) | Younger age at seizure onset |
| Low seizure severity (n=5): 105.0 (range, 71–126) | Persistent seizure after surgery | |||
| High seizure severity (n=3): 75.3 (range, 70–80) | High seizure severity after surgery | |||
| Faramand et al. (2018) [15] | 90 | Preoperative FSIQ | 81 (IQR, 71–95) | Younger age at seizure onset |
| Longer duration of epilepsy | ||||
| 41 | Postoperative FSIQ | 86 (IQR, 71–100) | Low preoperative FSIQ | |
| García-Fernández et al. (2011) [52] | 21 | Preoperative FSIQ | 85.2±21.9 | Younger age at seizure onset |
| Drug-resistant epilepsy before surgery | ||||
| Postoperative FSIQ | 88.6±17.7 | None | ||
| Giulioni et al. (2017) [16] | Unknown | Preoperative NP test | Normal vs. pathologic (deficit) | Longer duration of epilepsy |
| Ko et al. (2019) [54] | 58 | Preoperative FSIQ | 78.9±27.1 | Longer duration of epilepsy |
| 42 | Postoperative FSIQ | 80.9±28.7 | Low preoperative FSIQ | |
| Ramantani et al. (2014) [55] | 25 | Preoperative FSIQ | 93.0±21.8 | Longer duration of epilepsy |
| Preoperative VIQ | 95.9±13.8 | Longer duration of epilepsy | ||
| Preoperative PIQ | 101.2±15.5 | Younger age at seizure onset | ||
| 24 | Postoperative FSIQ | 91.7±21.6 | Low preoperative FSIQ |
Values are presented as mean (range), median (interquartile range), or mean±standard deviation.
FSIQ, full-scale intelligence quotient; NP, neuropsychological; VIQ, verbal intelligence quotient; PIQ, performance intelligence quotient.