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. 2020 Apr 11;12(4):945. doi: 10.3390/cancers12040945

Figure 8.

Figure 8

Dex promotes colitis-associated tumorigenesis. (A) The structural schematics of dexamethasone (Dex)-treated mice and the induction of colitis-associated tumorigenesis. (B) Colon tumors in control (phosphate buffer saline; PBS) or Dex-treated mice 70 days after the injection of azoxymethane (AOM). (C,D) The number and size of colon tumors in control or Dex-treated mice. (E) The number of colon tumors with the indicated treatments. Representative results are based on one of three independent experiments performed with similar results. The data are presented as the mean ± SD (n = 10–12 mice per group). Statistical significance was measured by one-way ANOVA for comparisons among multiple groups and Student’s unpaired t test for comparisons between two groups. *P < 0.05 and ***P < 0.001, compared with the indicated groups.