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OSMF tissue samples have increased RNA expression of various TGF-β isoforms: Quantitative PCR (qPCR) analysis of TGFβ1, TGFβ2, and TGFβ3 mRNA was done. As shown, fold change gene expression of respective isoforms was calculated ad presented as the histogram. TGF-β1 levels were significantly higher in OSMF as compared to normal. Similarly, TGF-β2 and TGF-β3 expression were also moderately increased in OSMF.
