Table 1.

Descriptive statistics of comparison of IL-1β levels on control and experimental sites.

Group 1 (Aligner group)	Experimental site		Control site
IL-1β	Mean	SD	Mean	SD	Mean difference	t-test value	p-value
Day 0	6.92	0.33	6.61	0.55	0.29	1.856	0.094
Day 1	15.64	0.84	6.19	0.88	8.25	20.564	<0.001*
Day 3	10.67	1.61	6.04	0.57	5.18	16.083	<0.001*
Day 7	7.93	1.58	5.81	0.96	2.76	8.157	<0.001*
Day 21	7.43	1.40	6.19	0.41	2.47	8.806	<0.001*
Unpaired t-test					* Significant difference