Table 1:
Participant Demographics
| Diagnosis | MDD | BD | P-value* | Control |
|---|---|---|---|---|
| N N=23 participants (N=30 total scans**) |
11 | 8 | -- | 4 |
| Age (SD) | 34.5 (12.8) | 31.3 (14.5) | 0.63 | 22.0 (4.1) |
| Number Female/Male (% Female/% Male) |
4/7 (36%/64%) |
4/4 (50%/50%) |
0.55 | 4/0 (100%/0%) |
| Screening HDRS-17 (SD) | 23.6 (4.8) | 22.2 (3.7) | 0.45 | 1.5 (0.6) |
| HDRS-24 Pre-Treatment (SD) | 27.4 (6.5) | 28.6 (3.9) | 0.60 | -- |
| HDRS-24 Post-Treatment (SD) | 16.6 (12.1) | 16.4 (10.5) | 0.98 | -- |
MDD: major depressive disorder, BD: bipolar disorder, SD: standard deviation, HDRS: Hamilton Depression Rating Scale, 17 or 24 Item
*
Calculated by t-test for continuous variables, chi-square for categorical variables. P-values only computed across MDD and BD groups based on small sample (N=4) and different variables in control group.
**
2 participants with BD and 5 with MDD received pre- and post-treatment PET and EEG, making the total sample size 30 even though there were 23 total participants.