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. 2020 May 28;22:58. doi: 10.1186/s13058-020-01292-9

Table 4.

Maximum slope and bolus arrival time according to invasive cancer characteristics

No. of lesions Maximum slope (mmol/s) Bolus arrival time (s)
Median IQR P value Median IQR P value
Tumor grade 111 0.552 0.025*
 Grade 3 56 (50) 0.034 0.022–0.054 21.3 19.3–23.4
 Grade 1 or 2 55 (50) 0.026 0.015–0.045 22.5 20.8–25.2
Histopathology 118 0.133 0.002*
 IDC 98 (83) 0.030 0.019–0.054 21.6 19.6–23.6
 ILC 20 (17) 0.028 0.013–0.049 23.7 21.8–25.9
Molecular subtype 124 0.361 < 0.001*
 HER2+ type or triple negative type 33 (27) 0.049 0.028–0.059 19.9 17.9–22.3
 Luminal type 91 (73) 0.027 0.017–0.045 22.5 20.7–24.8
Lymph node metastasis status 121 0.467 0.714
 Positive 57 (47) 0.030 0.016–0.051 21.9 20.2–23.8
 Negative 64 (53) 0.030 0.022–0.055 21.9 19.7–23.8
Oncotype DX recurrence score 45 0.538 0.633
 High/intermediate risk 15 (33) 0.032 0.025–0.049 22.2 20.2–24.7
 Low risk 30 (67) 0.026 0.015–0.046 21.7 20.4–23.7

MS maximum slope, BAT bolus arrival time, IQR interquartile range, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma

*P < 0.05

Data in parentheses are percentages

‡Molecular subtype are classified as follows: triple negative type [hormone receptor negative, HER2 negative], HER2 type [HER2 positive regardless of the hormone receptor positivity/negativity], or luminal type [hormone receptor positive, HER2 negative]