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. 2020 May 28;19:69. doi: 10.1186/s12933-020-01042-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Changes in LV function and geometry by SGLT2i according to the types of HF. The changes in echocardiographic parameters were compared between subgroups divided according to the types of HF (HFrEF vs. HFpEF) and the use of SGLT2i: a LV-EF, b LV-GLS, c LV-EDD, d LV-EDV, e mitral E/e′ ratio, and f PASP. Bars represent the median with interquartile range (Q1–Q3). Intra-group and inter-group comparisons were performed with paired t-test generalized linear model for repeated measure analysis, respectively. Abbreviations as in Figs. 1 and 2