Table 3.

Patient-reported anxiety (narrative synthesis)

#	Study, year	VAS	DAS	Other scale
1	Dantas, 2017 [2]	NA	Unclear findings on anxiety: the data suggested a period effect that was not tested and was not removed by the design due to different sequence size	NA
2	Smiley, 2014 [12]	The study was underpowered (suggesting lower anxiety with Midazolam vs. placebo)	NA	NA
3	Pereira Santos, 2013 [10]	NA	Unclear findings on anxiety: the data suggested a period effect that was not tested and was not removed by the design due to different sequence size	NA
4	Studer, 2012 [16]	No statistically significant difference between Midazolam vs. Clonidine	NA	NA
6	Fong, 2005 [18]	No statistically significant difference in the increase in anxiety score during operation between remifentanil vs. placebo	NA	NA
7	Ganzberg, 2005 [9]	The study was underpowered (suggesting lower anxiety with Zaleplon vs. Triazolam)	NA	NA
9	Manani, 2004 [20]	Lower anxiety with Midazolam 2 mg vs. 1 mg	Lower anxiety with Midazolam 2 mg vs. 1 mg	NA
10	Leitch, 2004 [4]	Lower anxiety with Propofol vs. Midazolam	NA	NA
11	Dionne, 2001 [8]	NA	NA	Lower anxiety with any intervention group vs. placebo; lower intraoperative anxiety with Fentanyl + Midazolam vs. Midazolam; lowest anxiety with Fentanyl + Midazolam + Methohexital vs. any other group
12	Bell, 2000 [21]	NA	Lower anxiety with Midazolam vs. none	NA
13	Milgrom, 1994 [22]	NA	NA	Lower anxiety with Fentanyl + Midazolam or with Fentanyl + Midazolam+ Methohexital + Methohexital
14	Stopperich, 1993 [23]	Lower anxiety with triazolam vs. placebo	Lower anxiety with triazolam vs. placebo	NA
15	Luyk, 1992 [24]	No statistically significance different between midazolam vs. placebo	NA	NA
16	Luyk, 1991 [25]	Lower anxiety with midazolam vs. placebo	NA	NA
17	O’Boyle, 1987 [26]	Lower anxiety with midazolam vs. diazepam	NA	No statistically significance different between midazolam vs. diazepam