Table 2.

Univariate and multivariate analyses for overall survival.

Variable	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)	P-value	Hazard ratio (95% CI)	P-value
Gender: (Male)	1.123 (0.806–1.565)	0.493
Age: (years>45)	1.579 (1.143–2.181)	0.006
Location: (Supratentorial)	1.126 (0.551–2.298)	0.745
WHO Grade: (High)	2.643 (1.750–3.992)	<0.001	2.270 (1.453–3.547)	<0.001
IDH: (Mutated)	0.347 (0.238–0.506)	<0.001	0.606 (0.393–0.934)	0.023
1p/19q: (Co-deleted)	0.307 (0.156–0.603)	0.001	0.267 (0.124–0.572)	0.001
ATRX: (Mutated)	0.734 (0.529–1.017)	0.063
TERTp: (Mutated)	1.921 (1.380–2.675)	<0.001	2.015 (1.412–2.875)	< 0.001
MGMTp: (Methylated)	0.525 (0.377–0.731)	<0.001	0.450 (0.320–0.633)	< 0.001
P53: (>10%)	1.249 (0.886–1.762)	0.204
PHH3: (>5)	1.735 (1.227–2.454)	0.002
Ki67: (>10%)	2.293 (1.444–3.639)	<0.001
LGALS3: (High)	1.846 (1.331–2.561)	<0.001	1.537 (1.204–1.987)	0.031

Method = Forward Stepwise (Conditional LR). Bold values represent p < 0.05.