Table 1. Effect of Phyllanthin and D8 on HCV RNA Replication Ex Vivo in Rep2a and Cell Viability Ex Vivoa.
HCV RNA replication in Rep2a cell line | cell viability (MTT assay) | |
---|---|---|
compound | EC50 (μM) | CC50 (mM) |
phyllanthin | 250 | 5.0 |
D8 | 75 | >5.0 |
Note: EC50 = 50% of effective concentration; CC50: 50% of cellular cytotoxicity.