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. 2020 May 14;5(20):11553–11562. doi: 10.1021/acsomega.0c00786

Table 1. Effect of Phyllanthin and D8 on HCV RNA Replication Ex Vivo in Rep2a and Cell Viability Ex Vivoa.

  HCV RNA replication in Rep2a cell line cell viability (MTT assay)
compound EC50 (μM) CC50 (mM)
phyllanthin 250 5.0
D8 75 >5.0
a

Note: EC50 = 50% of effective concentration; CC50: 50% of cellular cytotoxicity.