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IC50 (μM) of Raloxifene and the Most Effective Analogsa
| FpL2-6 | H11G11 | Rg3GUS | Rh2GUS | |
|---|---|---|---|---|
| raloxifene | 78 ± 9 | 100 ± 5 | 13 ± 2 | 13 ± 3 |
| UNC7084 | 18 ± 3 | 16 ± 3 | 5 ± 1 | 7 ± 3 |
| UNC7087 | 15 ± 1 | 16 ± 1 | 4 ± 1 | 2 ± 1 |
| UNC7159 | 13 ± 1 | 14 ± 1 | 7 ± 2 | 3 ± 1 |
Data are presented in micromolar as the average of 3 biological replicates ± SEM.
